This paper explores the relationship between early modern English Puritanism and Reformed orthodoxy through a fresh examination of three ministers who have been described as Puritans: John Owen, Richard Baxter, and John Goodwin. By assessing their attitudes toward the Bible and specifically the doctrine of justification, this paper uncovers an evolving consensus of orthodox thought in the period. Their attitudes and approaches to doctrine and church tradition led to diverse interpretations and directions in the codification of their religion. Their theological (...) interpretations reflect an inherent pattern of diversity within English Puritanism, especially in its attitudes towards the formation of orthodoxy. The relation of Reformed orthodoxy to Puritanism, then, is more complex than older modes of scholarship have allowed. For the Puritan mainstream, Reformed orthodoxy served as a theological compass and thermostat that tested ideas and was to govern both the direction and temperament of Reformed doctrine. For those outside the pale, such orthodoxy and their alleged disloyalty to the Bible and Reformed church tradition was vehemently contested. (shrink)

This essay examines the doctrine of divine omnipresence. I begin by presenting three desiderata for an adequate account of omnipresence. Four accounts are analyzed in light of these desiderata, two in the tradition and two in contemporary philosophical theology. I argue that none succeed in providing an adequate account of divine omnipresence. As an alternative, I offer a paradoxical account of omnipresence, arguing that one can be rational in affirming that what appears to be a doctrine afflicted by apparent contradiction (...) is in fact merely a paradox. I explain what makes affirmations of paradoxical doctrines rational, why omnipresence should be understood as a paradox, and discuss a similar account of omnipresence in the writings of Pseudo-Dionysius the Areopagite. (shrink)

Sex steroids, through their receptors, have potent effects on the signal pathways involved in osteogenic or myogenic differentiation. However, a considerable segment of those signal pathways has a prominent role in epithelial neoplastic transformation. The capability to intervene locally has focused on specific ligands for the receptors. Nevertheless, many signals are mapped to interactions of steroid receptor motifs with heterologous regulatory proteins. Some of those proteins interact with the glucocorticoid receptor and other factors essential to cell fate. Interactions of steroid (...) receptor domain motifs with heterologous proteins affect specific target pathways; consequently, manipulation of specified protein modules complexed with steroid receptors may be a next major step for enhancing molecular targeted therapeutics. In the future, intervention at specific sections of receptor primary sequence may prove therapeutically more efficient in targeting pathways of choice than ligand selectivity can be. (shrink)

Interdisciplinarity is a notoriously difficult concept to define, and even harder to achieve in practice. All too often social approaches reduce science to an object of study, or conversely physical science approaches are invoked as a source of 'higher' truth. Drawing upon our experiences as ESRC-NERC PhD students within geography, we outline a paratactical approach that links disciplines by adjacency rather than hierarchy. Toppling the disciplinary hierarchy creates the potential for non-reductionistic dialogue between science and social science, but it also (...) raises a series of practical difficulties. These are considered around the themes of polyvocality, breadth over depth and (im)permanence. We suggest that while this kind of approach is increasingly encouraged by research funding bodies, it is less easily sustained within the everyday mechanics of the academic world. (C) 2006 Elsevier Ltd. All rights reserved. (shrink)

Many upper limb amputees experience an incessant, post-amputation “phantom limb pain” and report that their missing limbs feel paralyzed in an uncomfortable posture. One hypothesis is that efferent commands no longer generate expected afferent signals, such as proprioceptive feedback from changes in limb configuration, and that the mismatch of motor commands and visual feedback is interpreted as pain. Non-invasive therapeutic techniques for treating phantom limb pain, such as mirror visual feedback (MVF), rely on visualizations of postural changes. Advances in neural (...) interfaces for artificial sensory feedback now make it possible to combine MVF with a high-tech “rubber hand” illusion, in which subjects develop a sense of embodiment with a fake hand when subjected to congruent visual and somatosensory feedback. We discuss clinical benefits that could arise from the confluence of known concepts such as MVF and the rubber hand illusion, and new technologies such as neural interfaces for sensory feedback and highly sensorized robot hand testbeds, such as the “BairClaw” presented here. Our multi-articulating, anthropomorphic robot testbed can be used to study proprioceptive and tactile sensory stimuli during physical finger-object interactions. Conceived for artificial grasp, manipulation, and haptic exploration, the BairClaw could also be used for future studies on the neurorehabilitation of somatosensory disorders due to upper limb impairment or loss. A remote actuation system enables the modular control of tendon-driven hands. The artificial proprioception system enables direct measurement of joint angles and tendon tensions while temperature, vibration, and skin deformation are provided by a multimodal tactile sensor. The provision of multimodal sensory feedback that is spatiotemporally consistent with commanded actions could lead to benefits such as reduced phantom limb pain, and increased prosthesis use due to improved functionality and reduced cognitive burden. (shrink)

Until recently, it was widely assumed in societies with long-established, publicly funded school systems that school attendance served the interests of children, society, and parents alike. In the United States and other common-law jurisdictions, safeguarding and promoting the independent welfare and developmental interests of every child was a public responsibility under the parens patriae doctrine. Compulsory schooling laws enacted under parens patriae authority required all persons having care and control of a child to share their custodial authority with publicly certified (...) teachers for limited periods of time. By compelling all parents to send their children to school, the state ensured that all children had access to instruction and opportunities for social, economic, and civic participation beyond what their parents alone could provide. Parents were incidentally freer to manage the competing demands of domestic life and paid employment, and the enforcement of child labor laws was greatly facilitated by efforts to ensure school attendance. While compulsory schooling laws imposed obvious limits on the custodial authority of all parents for the sake of all children, they were rarely challenged on that basis. Not so today. (shrink)

Forest tenure reforms are occurring in many developing countries around the world. These reforms typically include devolution of forest lands to local people and communities, which has attracted a great deal of attention and interest. While the nature and level of devolution vary by country, all have potentially important implications for resource allocation, local ecosystem services, livelihoods and climate change. This book helps students, researchers and professionals to understand the importance and implications of these reforms for local environmental quality, climate (...) change, and the livelihoods of villagers, who are often poor. It is shown that local forest management can often be more successful than top-down management of common pool forest resources. The relationship of local forest tenure reform to the important climate change initiative REDD+ is also considered. The work includes a number of generic chapters and also detailed case studies from China, Ethiopia, Kenya, Nepal, Tanzania and Uganda. Using specific examples and a wide variety of disciplinary perspectives, including quantitative and qualitative analytical methods, the book provides an authoritative and critical picture of local forest reforms in light of the key challenges humanity faces today. (shrink)